| Asian University for Women Support Foundation | Humanities Program | 03/11/22 | $1,000,000 | Cambridge, MA, United States | Higher Learning |
| Tougaloo College | Critical Collections | 03/11/22 | $550,000 | Tougaloo, MS, United States | Arts and Culture |
| National Trust for Historic Preservation in the United States | African American Cultural Heritage Action Fund | 03/11/22 | $7,500,000 | Washington, DC, United States | Humanities in Place |
| National Park Foundation | Expanding the Boundaries of America250 | 03/11/22 | $13,431,000 | Washington, DC, United States | Higher Learning |
| Pomona College | New Directions Fellowship: Egyptology: An African Perspective on Antiquity | 03/11/22 | $300,000 | Claremont, CA, United States | Higher Learning |
| University of Michigan | New Directions Fellowship: An Archaeology of Wind: Engineering Retraining to Explore Prehistoric Effects of an Invisible Force | 03/11/22 | $204,000 | Ann Arbor, MI, United States | Higher Learning |
| White Snake Projects, Inc. | Uplifting the Voices of Opera Artists | 03/11/22 | $750,000 | Brookline, MA, United States | Arts and Culture |
| University of Illinois at Urbana-Champaign | Intersectional Studies | 03/11/22 | $594,500 | Champaign, IL, United States | Higher Learning |
| Indiespace, Inc. | Services for Artists | 03/11/22 | $350,000 | Astoria, NY, United States | Arts and Culture |
| Metropolitan Museum of Art | Critical Collections | 03/11/22 | $2,000,000 | New York, NY, United States | Arts and Culture |
| Association of Tribal Archives, Libraries, and Museums | Going Home: Returning Material Culture to Indigenous Communities | 03/11/22 | $250,000 | Oklahoma City, OK, United States | Arts and Culture |
| Museum of African American History, Inc. | Expanding the American Story | 03/11/22 | $1,000,000 | Boston, MA, United States | Humanities in Place |
| Cheyenne River Youth Project, Inc. | Waniyetu Wowapi Institute and Art Park | 03/11/22 | $750,000 | Eagle Butte, SD, United States | Humanities in Place |
| University of Utah | Pacific Island Studies Growth and Outreach II | 03/11/22 | $1,000,000 | Salt Lake City, UT, United States | Higher Learning |
| School for Advanced Research | Mellon/SAR Postdoctoral/Doctoral Fellowships Phase II | 03/11/22 | $429,000 | Santa Fe, NM, United States | Higher Learning |
| Hunter College | The Mellon Public Humanities Scholars and Social Justice Program | 03/11/22 | $850,000 | New York, NY, United States | Higher Learning |
| Indiana University | New Directions Fellowship: Contemporary Latinx Opera: A New Direction for Art and Performance | 03/11/22 | $215,000 | Bloomington, IN, United States | Higher Learning |
| University of Virginia | New Directions Fellowship: The Economic Afterlife of Slavery in America | 03/11/22 | $262,000 | Charlottesville, VA, United States | Higher Learning |
| The Industry Productions, Inc. | Uplifting the Voices of Opera Artists | 03/11/22 | $1,000,000 | Los Angeles, CA, United States | Arts and Culture |
| University of Richmond | Distant Viewing Toolkit | 03/11/22 | $485,000 | Richmond, VA, United States | Public Knowledge |
| Foundation for Independent Artists, Inc. | nora chipaumire - Infrastructure, Independence, Sustainability | 03/11/22 | $955,000 | New York, NY, United States | Arts and Culture |
| Allied Media Projects, Inc. | Critical Minded | 03/11/22 | $1,292,500 | Detroit, MI, United States | Arts and Culture |
| Curtin University | Open Access E-book Usage Data Trust - Data Analytics | 03/11/22 | $750,000 | Perth, Australia | Public Knowledge |
| Illinois Humanities Council | Envisioning Justice | 03/11/22 | $600,000 | Chicago, IL, United States | Other |
| Wideman-Davis Dance of New York, Inc. | Migratuse Reimagined | 03/11/22 | $1,954,000 | Columbia, SC, United States | Other |
