| New Music USA, Inc. | Online Media Programs | 03/19/10 | $150,000 | New York, NY, United States | Arts and Culture |
| University of Cape Town | Research Bridges [Bond] | 03/19/10 | $300,000 | Cape Town, South Africa | Past Programs |
| Real Jardin Botanico de Madrid | Plants Initiative | 03/19/10 | $110,000 | Madrid, Spain | Past Programs |
| Royal Botanic Gardens, Kew | Plants Initiative | 03/19/10 | $234,000 | Richmond, United Kingdom | Past Programs |
| Linnean Society of London | Plants Initiative | 03/19/10 | $104,000 | London, United Kingdom | Past Programs |
| Henry E. Huntington Library & Art Gallery | Distinguished Fellowship | 03/19/10 | $500,000 | San Marino, CA, United States | Higher Learning |
| Indiana University | New Directions Fellowships [Leite] | 03/19/10 | $297,000 | Bloomington, IN, United States | Higher Learning |
| University of Toronto | New Directions Fellowships [Saleh] | 03/19/10 | $357,000 | Toronto, Ontario, Canada | Higher Learning |
| Five Colleges, Incorporated | Self-Instructional Language Program | 03/19/10 | $498,000 | Amherst, MA, United States | Higher Learning |
| Lawrence University | Faculty Mentorship Program | 03/19/10 | $525,000 | Appleton, WI, United States | Higher Learning |
| St. John’s College (Annapolis) | Senior President: Biology Curriculum Redesign | 03/19/10 | $250,000 | Annapolis, MD, United States | Higher Learning |
| Macalester College | Mid-Career President: Fine Arts & Global Citizenship | 03/19/10 | $150,000 | Saint Paul, MN, United States | Higher Learning |
| Stanford University | Mellon Mays Undergraduate Fellowship Program - Additional Years Support | 03/19/10 | $123,800 | Stanford, CA, United States | Higher Learning |
| Wesleyan University | Mellon Mays Undergraduate Fellowship Program - Additional Years Support | 03/19/10 | $123,800 | Middletown, CT, United States | Higher Learning |
| Connecticut College | Mellon Mays Undergraduate Fellowship Program - 10% Increase | 03/19/10 | $22,500 | New London, CT, United States | Higher Learning |
| University of the Western Cape | Mellon Mays Undergraduate Fellowship Program - 10% Increase | 03/19/10 | $22,500 | Bellville, South Africa | Higher Learning |
| University of the Western Cape | Visiting Fellows | 03/19/10 | $200,000 | Bellville, South Africa | International Higher Education and Strategic Projects |
| The Society for Classical Studies | Enhancing APh Online | 03/19/10 | $215,000 | Philadelphia, PA, United States | Public Knowledge |
| Columbia University | Developing a Jazz Discographic Database | 03/19/10 | $155,000 | New York, NY, United States | Public Knowledge |
| Foundation of the American Institute for Conservation of Historic and Artistic Works, Inc. | Photograph Conservation - State Hermitage Museum | 03/19/10 | $3,460,000 | Washington, DC, United States | Arts and Culture |
| New York Public Radio | WQXR/Q2 | 03/19/10 | $700,000 | New York, NY, United States | Arts and Culture |
| Oregon Shakespeare Festival Association, Inc. | American Revolutions Project | 03/19/10 | $600,000 | Ashland, OR, United States | Arts and Culture |
| Creative Capital Foundation | Loan Fund for Performing Artists | 03/19/10 | $250,000 | New York, NY, United States | Arts and Culture |
| University of Helsinki | Plants Initiative | 03/19/10 | $114,000 | Helsinki, Finland | Past Programs |
| New York Botanical Garden | Plants Initiative | 03/19/10 | $250,000 | Bronx, NY, United States | Past Programs |
